ML12B_HUMAN

Source: hRBCD ; ID: IPI00033494
PM19886704
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: MYL12B , MRLC2, MYLC2B
Protein names and data: ML12B_HUMAN , Myosin regulatory light chain 12B , MLC-2A; MLC-2; Myosin regulatory light chain 2-B, smooth muscle isoform; Myosin regulatory light chain 20 kDa; MLC20; Myosin regulatory light chain MRLC2; SHUJUN-1 Lenght: 172 a.a.
Mass: 19779 Da
fasta formatted sequence

Function: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity).
Tissue specificity: Ubiquitously expressed in various hematopoietic cells.

Genetic variants

Database cross-references

UniProt: O14950
Ensembl: ENST00000237500
Ensembl: ENST00000400175
Ensembl: ENST00000581193
Ensembl: ENST00000584539
neXtProt: NX_O14950
Antibodypedia: O14950 (may not find the protein thus also not any antibody)
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