Source: BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: MMP9 , CLG4B
Protein names and data: MMP9_HUMAN , Matrix metalloproteinase-9; MMP-9; , 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB; 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9; Flags: Precursor Lenght: 707 a.a.
Mass: 78458 Da
fasta formatted sequence

Function: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Catalytic activity: Cleavage of gelatin types I and V and collagen types IV and V.
Cellular location: Secreted, extracellular space, extracellular matrix (Probable).
Tissue specificity: Produced by normal alveolar macrophages and granulocytes.

Genetic variants

Database cross-references

UniProt: P14780
Ensembl: ENST00000372330
MIM: 120361
MIM: 603932
MIM: 613073
neXtProt: NX_P14780
Antibodypedia: P14780 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.