Source: hRBCD ; ID: IPI00008338
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: ABCC1 , MRP, MRP1
Protein names and data: MRP1_HUMAN , Multidrug resistance-associated protein 1 , ATP-binding cassette sub-family C member 1; Leukotriene C(4) transporter; LTC4 transporter Lenght: 1531 a.a.
Mass: 171591 Da
fasta formatted sequence

Function: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Cellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Lung, testis and peripheral blood mononuclear cells.

Genetic variants

Database cross-references

UniProt: P33527
Ensembl: ENST00000345148
Ensembl: ENST00000346370
Ensembl: ENST00000349029
Ensembl: ENST00000351154
Ensembl: ENST00000399408
Ensembl: ENST00000399410
MIM: 158343
neXtProt: NX_P33527
Antibodypedia: P33527 (may not find the protein thus also not any antibody)
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