MRP6_HUMAN

Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: ABCC6 , ARA, MRP6
Protein names and data: MRP6_HUMAN , Multidrug resistance-associated protein 6 , ATP-binding cassette sub-family C member 6; Anthracycline resistance-associated protein; Multi-specific organic anion transporter E; MOAT-E Lenght: 1503 a.a.
Mass: 164906 Da
fasta formatted sequence

Function: May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS).
Disease:
Cellular location: Basolateral cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed in kidney and liver. Very low expression in other tissues.

Genetic variants

Database cross-references

UniProt: O95255
Ensembl: ENST00000205557
Ensembl: ENST00000575728
MIM: 264800
MIM: 603234
MIM: 614473
neXtProt: NX_O95255
Antibodypedia: O95255 (may not find the protein thus also not any antibody)
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