RBCC Red Blood Cell Collection

MUC2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: MUC2 , SMUC
Protein names and data: MUC2_HUMAN , Mucin-2; MUC-2 , Intestinal mucin-2; Flags: Precursor Lenght: 5179 a.a.
Mass: 540300 Da
fasta formatted sequence
Function: Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.
Cellular location: Secreted. Note=In the intestine, secreted into the inner and outer mucus layers (By similarity).
Tissue specificity: Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.

Genetic variants

The number of repeats is highly polymorphic and varies among different alleles.

58 - 58 L -> P (in dbSNP:rs2856111). VAR_056582 2856111
116 - 116 V -> M (in dbSNP:rs11825977). VAR_056583 11825977
832 - 832 G -> S (in dbSNP:rs11245936). VAR_056584 11245936
1619 - 1619 S -> R (in dbSNP:rs11245947). VAR_059531 11245947
1689 - 1689 P -> L (in dbSNP:rs11245949). VAR_059532 11245949
1768 - 1768 P -> H (in dbSNP:rs34493663). VAR_061487 34493663
2154 - 2154 I -> T (in dbSNP:rs6421972). VAR_059533 6421972
2524 - 2524 T -> P (in dbSNP:rs7480563). VAR_059534 7480563
2524 - 2524 T -> S (in dbSNP:rs7480563). VAR_059535 7480563
2653 - 2653 Q -> L (in dbSNP:rs7126405). VAR_059536 7126405
2653 - 2653 Q -> P (in dbSNP:rs7126405). VAR_059537 7126405

Database cross-references

UniProt: Q02817
Ensembl: ENST00000359061
MIM: 158370
neXtProt: NX_Q02817
Antibodypedia: Q02817 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.

© Hegelab and Biomembrane 2013; Powered by TurboGears 2