MVD1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: MVD , MPD
Protein names and data: MVD1_HUMAN , Diphosphomevalonate decarboxylase; 4.1.1.33 , Mevalonate (diphospho)decarboxylase; MDDase; Mevalonate pyrophosphate decarboxylase Lenght: 400 a.a.
Mass: 43405 Da
fasta formatted sequence
Function: Performs the first committed step in the biosynthesis of isoprenes.
Catalytic activity: ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO(2).
Pathway: Steroid biosynthesis; cholesterol biosynthesis.
Tissue specificity: Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta.

Genetic variants

Database cross-references

UniProt: P53602
Ensembl: ENST00000301012
MIM: 603236
neXtProt: NX_P53602
Antibodypedia: P53602 (may not find the protein thus also not any antibody)
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