MYH9_HUMAN

Source: PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: MYH9
Protein names and data: MYH9_HUMAN , Myosin-9 , Cellular myosin heavy chain, type A; Myosin heavy chain 9; Myosin heavy chain, non-muscle IIa; Non-muscle myosin heavy chain A; NMMHC-A; Non-muscle myosin heavy chain IIa; NMMHC II-a; NMMHC-IIA Lenght: 1960 a.a.
Mass: 226532 Da
fasta formatted sequence

Function: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10.
Disease:
Cellular location: Cytoplasm, cytoskeleton (By similarity). Cytoplasm, cell cortex (By similarity). Note=Colocalizes with actin filaments at lamellipodia margins and at the leading edge of migrating cells.
Tissue specificity: In the kidney, expressed in the glomeruli. Also expressed in leukocytes.

Genetic variants

Database cross-references

UniProt: P35579
Ensembl: ENST00000216181
MIM: 153640
MIM: 153650
MIM: 155100
MIM: 160775
MIM: 600208
MIM: 603622
MIM: 605249
neXtProt: NX_P35579
Antibodypedia: P35579 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.