MYLK2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: MYLK2
Protein names and data: MYLK2_HUMAN , Myosin light chain kinase 2, skeletal/cardiac muscle; MLCK2; 2.7.11.18 Lenght: 596 a.a.
Mass: 64685 Da
fasta formatted sequence

Function: Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain.
Catalytic activity: ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate.
Disease:
Cellular location: Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Tissue specificity: Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue.

Genetic variants

Database cross-references

UniProt: Q9H1R3
Ensembl: ENST00000375985
Ensembl: ENST00000375994
MIM: 192600
MIM: 606566
neXtProt: NX_Q9H1R3
Antibodypedia: Q9H1R3 (may not find the protein thus also not any antibody)
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