NACAD_HUMAN
Source: PM23856902Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: NACAD , KIAA0363
Protein names and data: NACAD_HUMAN , NAC-alpha domain-containing protein 1 Lenght: 1562 a.a.
Mass: 161101 Da
fasta formatted sequence
Function: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).
Cellular location: Cytoplasm (By similarity). Nucleus (By similarity).
Genetic variants
Database cross-references
UniProt: O15069Ensembl: ENST00000490531
neXtProt: NX_O15069
Antibodypedia: O15069 (may not find the protein thus also not any antibody)
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