NAGK_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: NAGK
Protein names and data: NAGK_HUMAN , N-acetyl-D-glucosamine kinase; N-acetylglucosamine kinase; 2.7.1.59 , GlcNAc kinase Lenght: 344 a.a.
Mass: 37376 Da
fasta formatted sequence
Function: Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity.
Catalytic activity: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl- D-glucosamine 6-phosphate.
Pathway: Amino-sugar metabolism; N-acetylneuraminate degradation.
Tissue specificity: Ubiquitous.

Genetic variants

Database cross-references

UniProt: Q9UJ70
Ensembl: ENST00000244204
Ensembl: ENST00000455662
MIM: 606828
neXtProt: NX_Q9UJ70
Antibodypedia: Q9UJ70 (may not find the protein thus also not any antibody)
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