NASP_HUMAN

Source: PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: NASP
Protein names and data: NASP_HUMAN , Nuclear autoantigenic sperm protein; NASP Lenght: 788 a.a.
Mass: 85238 Da
fasta formatted sequence
Function: Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA (By similarity).
Cellular location: Cytoplasm (By similarity). Nucleus.
Tissue specificity: Isoform 1 is testis- and sperm-specific.

Genetic variants

Database cross-references

UniProt: P49321
Ensembl: ENST00000350030
Ensembl: ENST00000351223
Ensembl: ENST00000402363
Ensembl: ENST00000537798
MIM: 603185
neXtProt: NX_P49321
Antibodypedia: P49321 (may not find the protein thus also not any antibody)
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