NCDN_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: NCDN , KIAA0607
Protein names and data: NCDN_HUMAN , Neurochondrin Lenght: 729 a.a.
Mass: 78864 Da
fasta formatted sequence
Function: Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (By similarity). Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
Cellular location: Cytoplasm, cytosol. Cell projection, dendrite. Note=Localizes to somatic regions of neurons.
Tissue specificity: Abundantly expressed in whole adult brain and in all individual brain regions examined, including spinal cord. Weakly expressed in ovary, testis, fetal brain and small intestine.

Genetic variants

Database cross-references

UniProt: Q9UBB6
Ensembl: ENST00000356090
Ensembl: ENST00000373243
Ensembl: ENST00000373253
MIM: 608458
neXtProt: NX_Q9UBB6
Antibodypedia: Q9UBB6 (may not find the protein thus also not any antibody)
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