NPTN_HUMAN

Source: hRBCD ; ID: IPI00011578
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: NPTN , SDFR1, SDR1
Protein names and data: NPTN_HUMAN , Neuroplastin , Stromal cell-derived receptor 1; SDR-1; Flags: Precursor Lenght: 398 a.a.
Mass: 44387 Da
fasta formatted sequence
Function: Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity (By similarity).
Cellular location: Cell membrane; Single-pass type I membrane protein (Potential). Note=Enriched at postsynaptic density (By similarity).
Tissue specificity: Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level).

Database cross-references

UniProt: Q9Y639
Ensembl: ENST00000345330
Ensembl: ENST00000351217
Ensembl: ENST00000562924
Ensembl: ENST00000563691
MIM: 612820
neXtProt: NX_Q9Y639
Antibodypedia: Q9Y639 (may not find the protein thus also not any antibody)
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