NSF1C_HUMAN

Source: hRBCD ; ID: IPI00022830
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: NSFL1C , UBXN2C
Protein names and data: NSF1C_HUMAN , NSFL1 cofactor p47 , UBX domain-containing protein 2C; p97 cofactor p47 Lenght: 370 a.a.
Mass: 40573 Da
fasta formatted sequence
Function: Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro).
Cellular location: Nucleus (By similarity). Golgi apparatus, Golgi stack (By similarity). Chromosome (By similarity). Note=Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks (By similarity).

Genetic variants

Database cross-references

UniProt: Q9UNZ2
Ensembl: ENST00000216879
Ensembl: ENST00000353088
Ensembl: ENST00000381658
Ensembl: ENST00000476071
MIM: 606610
neXtProt: NX_Q9UNZ2
Antibodypedia: Q9UNZ2 (may not find the protein thus also not any antibody)
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