NSF_HUMAN

Source: hRBCD ; ID: IPI00006451
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: NSF
Protein names and data: NSF_HUMAN , Vesicle-fusing ATPase; 3.6.4.6 , N-ethylmaleimide-sensitive fusion protein; NEM-sensitive fusion protein; Vesicular-fusion protein NSF Lenght: 744 a.a.
Mass: 82594 Da
fasta formatted sequence
Function: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity).
Catalytic activity: ATP + H(2)O = ADP + phosphate.
Cellular location: Cytoplasm.

Genetic variants

Database cross-references

UniProt: P46459
Ensembl: ENST00000398238
MIM: 601633
neXtProt: NX_P46459
Antibodypedia: P46459 (may not find the protein thus also not any antibody)
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