NUDT5_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: NUDT5 , HSPC115
Protein names and data: NUDT5_HUMAN , ADP-sugar pyrophosphatase; 3.6.1.13 , 8-oxo-dGDP phosphatase; 3.6.1.58; Nucleoside diphosphate-linked moiety X motif 5; Nudix motif 5; YSA1H Lenght: 219 a.a.
Mass: 24328 Da
fasta formatted sequence
Function: Hydrolyzes with similar activities ADP-ribose ADP- mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
Catalytic activity: ADP-D-ribose + H(2)O = AMP + D-ribose 5- phosphate. ADP-sugar + H(2)O = AMP + alpha-D-aldose 5- phosphate. 8-oxo-dGDP + H(2)O = 8-oxo-dGMP + phosphate.
Tissue specificity: Widely expressed. Most abundant in liver.

Genetic variants

Database cross-references

UniProt: Q9UKK9
Ensembl: ENST00000491614
Ensembl: ENST00000537776
MIM: 609230
neXtProt: NX_Q9UKK9
Antibodypedia: Q9UKK9 (may not find the protein thus also not any antibody)
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