ODO2_HUMAN

Source: PM19886704
PM23856902
BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: DLST , DLTS
Protein names and data: ODO2_HUMAN , Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; 2.3.1.61 , 2-oxoglutarate dehydrogenase complex component E2; OGDC-E2; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2K; Flags: Precursor Lenght: 453 a.a.
Mass: 48755 Da
fasta formatted sequence
Function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
Catalytic activity: Succinyl-CoA + enzyme N(6)- (dihydrolipoyl)lysine = CoA + enzyme N(6)-(S- succinyldihydrolipoyl)lysine.
Pathway: Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.
Cellular location: Mitochondrion.

Genetic variants

Database cross-references

UniProt: P36957
Ensembl: ENST00000334220
MIM: 126063
neXtProt: NX_P36957
Antibodypedia: P36957 (may not find the protein thus also not any antibody)
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