Source: BSc_CH
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: DDOST , KIAA0115, OST48 , OK/SW-cl.45
Protein names and data: OST48_HUMAN , Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; DDOST 48 kDa subunit; Oligosaccharyl transferase 48 kDa subunit;; Flags: Precursor Lenght: 456 a.a.
Mass: 50801 Da
fasta formatted sequence

Function: Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.
Catalytic activity: Dolichyl diphosphooligosaccharide + [protein]- L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
Pathway: Protein modification; protein glycosylation.
Cellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Genetic variants

Database cross-references

UniProt: P39656
Ensembl: ENST00000375048
Ensembl: ENST00000602624
MIM: 602202
MIM: 614507
neXtProt: NX_P39656
Antibodypedia: P39656 (may not find the protein thus also not any antibody)
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