PDCL3_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PDCL3 , PhLP2A, VIAF1
Protein names and data: PDCL3_HUMAN , Phosducin-like protein 3 , HTPHLP; PhPL3; Viral IAP-associated factor 1; VIAF-1 Lenght: 239 a.a.
Mass: 27614 Da
fasta formatted sequence
Function: Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination.
Cellular location: Cytoplasm.
Tissue specificity: Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon.

Database cross-references

UniProt: Q9H2J4
Ensembl: ENST00000264254
MIM: 611678
neXtProt: NX_Q9H2J4
Antibodypedia: Q9H2J4 (may not find the protein thus also not any antibody)
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