RBCC Red Blood Cell Collection

PDIA2_HUMAN

Source: hRBCD ; ID: IPI00011571
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: PDIA2 , PDIP
Protein names and data: PDIA2_HUMAN , Protein disulfide-isomerase A2; 5.3.4.1 , Pancreas-specific protein disulfide isomerase; PDIp; Flags: Precursor Lenght: 525 a.a.
Mass: 58206 Da
fasta formatted sequence
Function: Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
Catalytic activity: Catalyzes the rearrangement of -S-S- bonds in proteins.
Cellular location: Endoplasmic reticulum lumen (By similarity).
Tissue specificity: Highly expressed in pancreas (at protein level).

Genetic variants

39 - 39 P -> S (in dbSNP:rs45455191). VAR_048087 45455191
119 - 119 T -> R (in dbSNP:rs45614840). VAR_048088 45614840
185 - 185 E -> K (in dbSNP:rs419949). VAR_048089 419949
286 - 286 T -> M (in dbSNP:rs2685127). VAR_048090 2685127
382 - 382 P -> A (in dbSNP:rs45529833). VAR_048091 45529833
388 - 388 R -> Q (in dbSNP:rs400037). VAR_048092 400037
502 - 502 P -> S (in dbSNP:rs1048786). VAR_048093 1048786

Database cross-references

UniProt: Q13087
Ensembl: ENST00000219406
Ensembl: ENST00000404312
MIM: 608012
neXtProt: NX_Q13087
Antibodypedia: Q13087 (may not find the protein thus also not any antibody)
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