PDIA6_HUMAN

Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PDIA6 , ERP5, P5, TXNDC7
Protein names and data: PDIA6_HUMAN , Protein disulfide-isomerase A6; 5.3.4.1 , Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7; Flags: Precursor Lenght: 440 a.a.
Mass: 48121 Da
fasta formatted sequence
Function: May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
Catalytic activity: Catalyzes the rearrangement of -S-S- bonds in proteins.
Cellular location: Endoplasmic reticulum lumen (By similarity). Cell membrane. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue specificity: Expressed in platelets (at protein level).

Genetic variants

Database cross-references

UniProt: Q15084
Ensembl: ENST00000272227
Ensembl: ENST00000404371
MIM: 611099
neXtProt: NX_Q15084
Antibodypedia: Q15084 (may not find the protein thus also not any antibody)
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