PGH2_HUMAN

Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PTGS2 , COX2
Protein names and data: PGH2_HUMAN , Prostaglandin G/H synthase 2; 1.14.99.1 , Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2; Flags: Precursor Lenght: 604 a.a.
Mass: 68996 Da
fasta formatted sequence
Function: Critical component of colonic mucosal wound repair (By similarity). Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
Catalytic activity: Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.
Pathway: Lipid metabolism; prostaglandin biosynthesis.
Cellular location: Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.

Genetic variants

Database cross-references

UniProt: P35354
Ensembl: ENST00000367468
MIM: 600262
neXtProt: NX_P35354
Antibodypedia: P35354 (may not find the protein thus also not any antibody)
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