PGTA_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: RABGGTA
Protein names and data: PGTA_HUMAN , Geranylgeranyl transferase type-2 subunit alpha; 2.5.1.60 , Geranylgeranyl transferase type II subunit alpha; Rab geranyl-geranyltransferase subunit alpha; Rab GG transferase alpha; Rab GGTase alpha; Rab geranylgeranyltransferase subunit alpha Lenght: 567 a.a.
Mass: 65072 Da
fasta formatted sequence
Function: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.
Catalytic activity: Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.

Genetic variants

Database cross-references

UniProt: Q92696
Ensembl: ENST00000216840
Ensembl: ENST00000399409
MIM: 601905
neXtProt: NX_Q92696
Antibodypedia: Q92696 (may not find the protein thus also not any antibody)
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