PHOP1_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PHOSPHO1
Protein names and data: PHOP1_HUMAN , Phosphoethanolamine/phosphocholine phosphatase; 3.1.3.75 Lenght: 267 a.a.
Mass: 29713 Da
fasta formatted sequence
Function: Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization.
Catalytic activity: O-phosphoethanolamine + H(2)O = ethanolamine + phosphate. Phosphocholine + H(2)O = choline + phosphate.
Tissue specificity: Expressed at sites of mineralization in bone and cartilage. Highly expressed in osteoblast cell line SaOS-2 which produces a mineralized matrix, but not in MG-63 cell line, which do not mineralize.

Database cross-references

UniProt: Q8TCT1
Ensembl: ENST00000310544
Ensembl: ENST00000413580
Ensembl: ENST00000514112
neXtProt: NX_Q8TCT1
Antibodypedia: Q8TCT1 (may not find the protein thus also not any antibody)
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