PI4KA_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PI4KA , PIK4, PIK4CA
Protein names and data: PI4KA_HUMAN , Phosphatidylinositol 4-kinase alpha; PI4-kinase alpha; PI4K-alpha; PtdIns-4-kinase alpha; 2.7.1.67 Lenght: 2044 a.a.
Mass: 231319 Da
fasta formatted sequence
Function: Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate.
Catalytic activity: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate.
Tissue specificity: Expressed ubiquitously. Highest levels in placenta and brain. Little or no expression in lung, liver, pancreas, testis or leukocytes.

Genetic variants

Database cross-references

UniProt: P42356
Ensembl: ENST00000414196
Ensembl: ENST00000572273
MIM: 600286
neXtProt: NX_P42356
Antibodypedia: P42356 (may not find the protein thus also not any antibody)
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