PLCB3_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: PLCB3
Protein names and data: PLCB3_HUMAN , 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 3.1.4.11 , Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3 Lenght: 1234 a.a.
Mass: 138799 Da
fasta formatted sequence

Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Cellular location: Membrane; Peripheral membrane protein.

Genetic variants

Database cross-references

UniProt: Q01970
Ensembl: ENST00000279230
Ensembl: ENST00000325234
Ensembl: ENST00000540288
MIM: 600230
neXtProt: NX_Q01970
Antibodypedia: Q01970 (may not find the protein thus also not any antibody)
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