PPCS_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PPCS , COAB
Protein names and data: PPCS_HUMAN , Phosphopantothenate--cysteine ligase; 6.3.2.5 , Phosphopantothenoylcysteine synthetase; PPC synthetase Lenght: 311 a.a.
Mass: 34005 Da
fasta formatted sequence
Function: Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine.
Catalytic activity: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + N-((R)-4'-phosphopantothenoyl)-L-cysteine.
Pathway: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.

Database cross-references

UniProt: Q9HAB8
Ensembl: ENST00000372561
Ensembl: ENST00000372562
Ensembl: ENST00000455780
MIM: 609853
neXtProt: NX_Q9HAB8
Antibodypedia: Q9HAB8 (may not find the protein thus also not any antibody)
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