PPIA_HUMAN

Source: hRBCD ; ID: IPI00006664
PM19886704
PM23856902
BSc_CH
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: PPIA , CYPA
Protein names and data: PPIA_HUMAN , Peptidyl-prolyl cis-trans isomerase A; PPIase A; 5.2.1.8 , Cyclophilin A; Cyclosporin A-binding protein; Rotamase A; Peptidyl-prolyl cis-trans isomerase A, N-terminally processed Lenght: 165 a.a.
Mass: 18012 Da
fasta formatted sequence
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0).
Cellular location: Cytoplasm. Secreted. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.

Database cross-references

UniProt: P62937
Ensembl: ENST00000468812
MIM: 123840
neXtProt: NX_P62937
Antibodypedia: P62937 (may not find the protein thus also not any antibody)
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