PRAF2_HUMAN

Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PRAF2 , JM4
Protein names and data: PRAF2_HUMAN , PRA1 family protein 2 Lenght: 178 a.a.
Mass: 19258 Da
fasta formatted sequence
Function: May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.
Cellular location: Endosome membrane; Multi-pass membrane protein (Probable).
Tissue specificity: Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non- neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.

Genetic variants

Database cross-references

UniProt: O60831
Ensembl: ENST00000376390
MIM: 300840
neXtProt: NX_O60831
Antibodypedia: O60831 (may not find the protein thus also not any antibody)
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