PRDX2_HUMAN

Source: hRBCD ; ID: IPI00027350
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: PRDX2 , NKEFB, TDPX1
Protein names and data: PRDX2_HUMAN , Peroxiredoxin-2; 1.11.1.15 , Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1 Lenght: 198 a.a.
Mass: 21892 Da
fasta formatted sequence
Function: Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
Catalytic activity: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.
Cellular location: Cytoplasm.

Genetic variants

Database cross-references

UniProt: P32119
Ensembl: ENST00000301522
Ensembl: ENST00000435703
MIM: 600538
neXtProt: NX_P32119
Antibodypedia: P32119 (may not find the protein thus also not any antibody)
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