PRDX3_HUMAN

Source: PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: PRDX3 , AOP1
Protein names and data: PRDX3_HUMAN , Thioredoxin-dependent peroxide reductase, mitochondrial; 1.11.1.15 , Antioxidant protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog; Flags: Precursor Lenght: 256 a.a.
Mass: 27693 Da
fasta formatted sequence
Function: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Catalytic activity: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.
Cellular location: Mitochondrion.

Genetic variants

Database cross-references

UniProt: P30048
Ensembl: ENST00000298510
MIM: 604769
neXtProt: NX_P30048
Antibodypedia: P30048 (may not find the protein thus also not any antibody)
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