PRDX6_HUMAN

Source: hRBCD ; ID: IPI00220301
PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: PRDX6 , AOP2, KIAA0106
Protein names and data: PRDX6_HUMAN , Peroxiredoxin-6; 1.11.1.15 , 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2; 3.1.1.-; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase; NSGPx; 1.11.1.9; Red blood cells page spot 12 Lenght: 224 a.a.
Mass: 25035 Da
fasta formatted sequence
Function: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Catalytic activity: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH. 2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
Cellular location: Cytoplasm. Lysosome (By similarity). Cytoplasmic vesicle (By similarity). Note=Also found in lung secretory organelles (By similarity).

Database cross-references

UniProt: P30041
Ensembl: ENST00000340385
MIM: 602316
neXtProt: NX_P30041
Antibodypedia: P30041 (may not find the protein thus also not any antibody)
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