Source: BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: PRG3 , MBPH , UNQ486/PRO1002
Protein names and data: PRG3_HUMAN , Proteoglycan 3 , Eosinophil major basic protein homolog; Prepro-major basic protein homolog; Prepro-MBPH; Flags: Precursor Lenght: 225 a.a.
Mass: 25406 Da
fasta formatted sequence

Function: Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.
Cellular location: Cytoplasmic granule. Note=Localized to the eosinophil secondary granule.
Tissue specificity: Expressed in bone marrow. Not detected in placenta.

Genetic variants

Database cross-references

UniProt: Q9Y2Y8
Ensembl: ENST00000287143
MIM: 606814
neXtProt: NX_Q9Y2Y8
Antibodypedia: Q9Y2Y8 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.