PRS6A_HUMAN

Source: hRBCD ; ID: IPI00018398
PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: PSMC3 , TBP1
Protein names and data: PRS6A_HUMAN , 26S protease regulatory subunit 6A , 26S proteasome AAA-ATPase subunit RPT5; Proteasome 26S subunit ATPase 3; Proteasome subunit P50; Tat-binding protein 1; TBP-1 Lenght: 439 a.a.
Mass: 49204 Da
fasta formatted sequence
Function: The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). In case of HIV-1 infection, suppresses Tat-mediated transactivation.
Cellular location: Cytoplasm (Potential). Nucleus (Potential). Cytoplasm, P-body (By similarity). Note=Colocalizes with TRIM5 in the cytoplasmic bodies (By similarity).

Database cross-references

UniProt: P17980
Ensembl: ENST00000298852
MIM: 186852
neXtProt: NX_P17980
Antibodypedia: P17980 (may not find the protein thus also not any antibody)
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