PRTN3_HUMAN

Source: BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: PRTN3 , MBN
Protein names and data: PRTN3_HUMAN , Myeloblastin; 3.4.21.76 , AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen; Flags: Precursor Lenght: 256 a.a.
Mass: 27807 Da
fasta formatted sequence
Function: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
Catalytic activity: Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.

Genetic variants

Database cross-references

UniProt: P24158
Ensembl: ENST00000234347
MIM: 177020
neXtProt: NX_P24158
Antibodypedia: P24158 (may not find the protein thus also not any antibody)
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