PSA1_HUMAN
Source: hRBCD ; ID: IPI00016832PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: PSMA1 , HC2, NU, PROS30, PSC2
Protein names and data: PSA1_HUMAN , Proteasome subunit alpha type-1; 3.4.25.1 , 30 kDa prosomal protein; PROS-30; Macropain subunit C2; Multicatalytic endopeptidase complex subunit C2; Proteasome component C2; Proteasome nu chain Lenght: 263 a.a.
Mass: 29556 Da
fasta formatted sequence
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells (By similarity).
Catalytic activity: Cleavage of peptide bonds with very broad specificity.
Cellular location: Cytoplasm. Nucleus.
Genetic variants
Database cross-references
UniProt: P25786Ensembl: ENST00000396393
Ensembl: ENST00000396394
Ensembl: ENST00000418988
MIM: 602854
neXtProt: NX_P25786
Antibodypedia: P25786 (may not find the protein thus also not any antibody)
Local full text data: click here