PSB4_HUMAN

Source: hRBCD ; ID: IPI00291936
PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: PSMB4 , PROS26
Protein names and data: PSB4_HUMAN , Proteasome subunit beta type-4; 3.4.25.1 , 26 kDa prosomal protein; HsBPROS26; PROS-26; Macropain beta chain; Multicatalytic endopeptidase complex beta chain; Proteasome beta chain; Proteasome chain 3; HsN3; Flags: Precursor Lenght: 264 a.a.
Mass: 29204 Da
fasta formatted sequence
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Catalytic activity: Cleavage of peptide bonds with very broad specificity.
Cellular location: Cytoplasm (By similarity). Nucleus (By similarity).

Genetic variants

Database cross-references

UniProt: P28070
Ensembl: ENST00000290541
MIM: 602177
neXtProt: NX_P28070
Antibodypedia: P28070 (may not find the protein thus also not any antibody)
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