PSD11_HUMAN

Source: hRBCD ; ID: IPI00105598
PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: PSMD11
Protein names and data: PSD11_HUMAN , 26S proteasome non-ATPase regulatory subunit 11 , 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5 Lenght: 422 a.a.
Mass: 47464 Da
fasta formatted sequence
Function: Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Cellular location: Nucleus (By similarity). Cytoplasm, cytosol (By similarity).
Tissue specificity: Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate.

Database cross-references

UniProt: O00231
Ensembl: ENST00000261712
Ensembl: ENST00000457654
MIM: 604449
neXtProt: NX_O00231
Antibodypedia: O00231 (may not find the protein thus also not any antibody)
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