PSMD2_HUMAN

Source: hRBCD ; ID: IPI00012268
PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: PSMD2 , TRAP2
Protein names and data: PSMD2_HUMAN , 26S proteasome non-ATPase regulatory subunit 2 , 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2 Lenght: 908 a.a.
Mass: 100200 Da
fasta formatted sequence

Function: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
Tissue specificity: Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta.

Genetic variants

Database cross-references

UniProt: Q13200
Ensembl: ENST00000310118
MIM: 606223
neXtProt: NX_Q13200
Antibodypedia: Q13200 (may not find the protein thus also not any antibody)
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