Source: hRBCD ; ID: IPI00179964
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: PTBP1 , PTB
Protein names and data: PTBP1_HUMAN , Polypyrimidine tract-binding protein 1; PTB , 57 kDa RNA-binding protein PPTB-1; Heterogeneous nuclear ribonucleoprotein I; hnRNP I Lenght: 531 a.a.
Mass: 57221 Da
fasta formatted sequence

Function: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.
Cellular location: Nucleus.

Database cross-references

UniProt: P26599
Ensembl: ENST00000349038
Ensembl: ENST00000356948
Ensembl: ENST00000394601
MIM: 600693
neXtProt: NX_P26599
Antibodypedia: P26599 (may not find the protein thus also not any antibody)
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