PTN23_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PTPN23 , KIAA1471
Protein names and data: PTN23_HUMAN , Tyrosine-protein phosphatase non-receptor type 23; 3.1.3.48 , His domain-containing protein tyrosine phosphatase; HD-PTP; Protein tyrosine phosphatase TD14; PTP-TD14 Lenght: 1636 a.a.
Mass: 178974 Da
fasta formatted sequence
Function: Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
Cellular location: Nucleus. Cytoplasm. Cytoplasmic vesicle. Endosome. Cytoplasm, cytoskeleton, cilium basal body. Early endosome.

Genetic variants

Database cross-references

UniProt: Q9H3S7
Ensembl: ENST00000265562
MIM: 606584
neXtProt: NX_Q9H3S7
Antibodypedia: Q9H3S7 (may not find the protein thus also not any antibody)
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