PUR4_HUMAN

Source: hRBCD ; ID: IPI00004534
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: PFAS , KIAA0361
Protein names and data: PUR4_HUMAN , Phosphoribosylformylglycinamidine synthase; FGAM synthase; FGAMS; 6.3.5.3 , Formylglycinamide ribotide amidotransferase; FGARAT; Formylglycinamide ribotide synthetase Lenght: 1338 a.a.
Mass: 144734 Da
fasta formatted sequence
Catalytic activity: ATP + N(2)-formyl-N(1)-(5-phospho-D- ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2- (formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate.
Pathway: Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5- phospho-D-ribosyl)glycinamide: step 1/2.
Cellular location: Cytoplasm (By similarity).

Genetic variants

Database cross-references

UniProt: O15067
Ensembl: ENST00000314666
MIM: 602133
neXtProt: NX_O15067
Antibodypedia: O15067 (may not find the protein thus also not any antibody)
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