Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: high (a blood group or CD marker) Search PubMed for
(RBC AND this entry)

Gene names: PVRL1 , HVEC, PRR1
Protein names and data: PVRL1_HUMAN , Poliovirus receptor-related protein 1 , Herpes virus entry mediator C; Herpesvirus entry mediator C; HveC; Herpesvirus Ig-like receptor; HIgR; Nectin-1; CD111; Flags: Precursor Lenght: 517 a.a.
Mass: 57158 Da
fasta formatted sequence

Function: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4. Functions as an entry receptor for herpes simplex virus and pseudorabies virus.
Cellular location: Isoform Alpha: Cell membrane; Single-pass type I membrane protein. Isoform Delta: Cell membrane; Single-pass type I membrane protein. Isoform Gamma: Secreted.

Database cross-references

UniProt: Q15223
Ensembl: ENST00000264025
Ensembl: ENST00000340882
Ensembl: ENST00000341398
MIM: 225060
MIM: 600644
neXtProt: NX_Q15223
Antibodypedia: Q15223 (may not find the protein thus also not any antibody)
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