PYRG2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CTPS2
Protein names and data: PYRG2_HUMAN , CTP synthase 2; 6.3.4.2 , CTP synthetase 2; UTP--ammonia ligase 2 Lenght: 586 a.a.
Mass: 65678 Da
fasta formatted sequence
Function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
Catalytic activity: ATP + UTP + L-glutamine = ADP + phosphate + CTP + L-glutamate.
Pathway: Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.

Database cross-references

UniProt: Q9NRF8
Ensembl: ENST00000359276
Ensembl: ENST00000380241
Ensembl: ENST00000443824
MIM: 300380
neXtProt: NX_Q9NRF8
Antibodypedia: Q9NRF8 (may not find the protein thus also not any antibody)
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