Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: RAB12
Protein names and data: RAB12_HUMAN , Ras-related protein Rab-12 Lenght: 244 a.a.
Mass: 27248 Da
fasta formatted sequence

Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor (By similarity).
Cellular location: Recycling endosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Lysosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Golgi apparatus membrane (By similarity).

Database cross-references

UniProt: Q6IQ22
Ensembl: ENST00000329286
neXtProt: NX_Q6IQ22
Antibodypedia: Q6IQ22 (may not find the protein thus also not any antibody)
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