RAB8B_HUMAN

Source: hRBCD ; ID: IPI00024282
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Membrane associated protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: RAB8B
Protein names and data: RAB8B_HUMAN , Ras-related protein Rab-8B; Flags: Precursor Lenght: 207 a.a.
Mass: 23584 Da
fasta formatted sequence
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).
Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.

Database cross-references

UniProt: Q92930
Ensembl: ENST00000321437
MIM: 613532
neXtProt: NX_Q92930
Antibodypedia: Q92930 (may not find the protein thus also not any antibody)
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