Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: RALB
Protein names and data: RALB_HUMAN , Ras-related protein Ral-B; Flags: Precursor Lenght: 206 a.a.
Mass: 23409 Da
fasta formatted sequence

Function: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis.
Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Note=During late cytokinesis localizes at the midbody.

Database cross-references

UniProt: P11234
Ensembl: ENST00000272519
Ensembl: ENST00000420510
MIM: 179551
neXtProt: NX_P11234
Antibodypedia: P11234 (may not find the protein thus also not any antibody)
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