RAP2B_HUMAN

Source: hRBCD ; ID: IPI00018364
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Membrane associated protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: RAP2B
Protein names and data: RAP2B_HUMAN , Ras-related protein Rap-2b; Flags: Precursor Lenght: 183 a.a.
Mass: 20504 Da
fasta formatted sequence
Function: Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.
Cellular location: Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Associated with red blood cells-released vesicles.
Tissue specificity: Expressed in red blood cells (at protein level).

Database cross-references

UniProt: P61225
Ensembl: ENST00000323534
MIM: 179541
neXtProt: NX_P61225
Antibodypedia: P61225 (may not find the protein thus also not any antibody)
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