Source: PM19886704
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: RAB22A , RAB22
Protein names and data: RB22A_HUMAN , Ras-related protein Rab-22A; Rab-22 Lenght: 194 a.a.
Mass: 21855 Da
fasta formatted sequence

Function: Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
Cellular location: Endosome membrane; Lipid-anchor (By similarity). Cell membrane; Lipid-anchor (By similarity). Early endosome. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.

Database cross-references

UniProt: Q9UL26
Ensembl: ENST00000244040
MIM: 612966
neXtProt: NX_Q9UL26
Antibodypedia: Q9UL26 (may not find the protein thus also not any antibody)
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