RBP10_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: RANBP10 , KIAA1464
Protein names and data: RBP10_HUMAN , Ran-binding protein 10; RanBP10 Lenght: 620 a.a.
Mass: 67257 Da
fasta formatted sequence
Function: Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway.
Cellular location: Cytoplasm, cytosol. Nucleus. Note=Predominantly cytoplasmic.
Tissue specificity: Broadly expressed, with highest levels in skeletal muscle.

Database cross-references

UniProt: Q6VN20
Ensembl: ENST00000317506
MIM: 614031
neXtProt: NX_Q6VN20
Antibodypedia: Q6VN20 (may not find the protein thus also not any antibody)
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